Straightforward synthesis of indolizidine alkaloid 167B |
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| Authors: | Sté phanie Gracia,Florence Popowycz |
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| Affiliation: | Institut de Chimie et Biochimie Moléculaires et Supramoléculaires, UMR-CNRS 5246, Equipe Catalyse Synthèse Environnement, Université de Lyon, Université Claude Bernard—Lyon 1, Bâtiment Curien, 43 Bd du 11 Novembre 1918, F-69622 Villeurbanne, France |
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| Abstract: | The synthetic access to indolizidines, substituted in C-5 position, was reported with good diastereoselectivity. The strategy developed was based on a key step of Michael addition associated with a Clauson-Kaas condensation. |
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| Keywords: | Alkaloids Indolizidines Michael addition Multi-step synthesis |
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