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Application of cyclic-1,3-diketones in domino and multicomponent reactions: facile route to highly functionalized chromeno[2,3-d]pyrimidinones and diazabenzo[b]fluorenones under solvent-free conditions
Authors:Ram Kumar
Institution:Department of Chemistry, Faculty of Science, Banaras Hindu University, Varanasi 221005, India
Abstract:A facile and efficient protocol for the synthesis of chromeno2,3-d]pyrimidinones and diazabenzob]fluorenones has been developed by one-pot three-component cyclocondensation of aldehydes, cyclic-1,3-diketones and 1,3-dimethylbarbituric acid in the presence of InCl3 or P2O5 under solvent-free conditions.
Keywords:Multicomponent reaction  Chromeno[2  3-d]pyrimidinones  Diazabenzo[b]fluorenones  InCl3  P2O5  Solvent-free conditions
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