Catalytic enantioselective tert-aminocyclization by asymmetric binary acid catalysis (ABC): stereospecific 1,5-hydrogen transfer |
| |
| Authors: | Chen Liujuan Zhang Long Lv Jian Cheng Jin-Pei Luo Sanzhong |
| |
| Affiliation: | Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China. |
| |
| Abstract: | Selective H transfer by ABC: A new asymmetric binary acid catalyst was developed to promote 1,5-H transfer specifically and stereoselectively in tert-aminocyclization reactions with excellent activity, high enantioselectivity, and broad substrate scope. The H atom (in red) was proven to transfer through a stereospecific suprafacial pathway (see scheme). |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
