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Studies on the Total Synthesis of the Repeat Unit of Candida kefyr IFO 0586 Strain
引用本文:Ping Yu DING, Cheng He ZHOU, Wu Yan ZHANG, Meng Shen CAI (Department of Bio-organic Chemistry,School of Pharmaceutical Sciences,Beijing Medical University,Beijing 100083). Studies on the Total Synthesis of the Repeat Unit of Candida kefyr IFO 0586 Strain[J]. 中国化学快报, 1998, 0(9)
作者姓名:Ping Yu DING   Cheng He ZHOU   Wu Yan ZHANG   Meng Shen CAI (Department of Bio-organic Chemistry  School of Pharmaceutical Sciences  Beijing Medical University  Beijing 100083)
作者单位:Department of Bio-organic Chemistry,School of Pharmaceutical Sciences,Beijing Medical University,Beijing 100083
摘    要:Ithasrecentlybeenreportedthatthea-linkedoligo-D-mannosylsidechainsofacell-wallD-marmanofthepathogenicyeastalbicansareinlargepartresponsiblefortheyeastcellbindingtothemarginalzoneofmousespleen',andthealkali-releaseda-linkedD-manno-oligosaccharidesisolatedfromaCandidaalbicanscell-wallD-mannanwerepotentinhibitorsoflymphoproliferationinducedbytheparentD-mannan'.Thesefactsseemofinterestfromtheviewpointofbothhost-parasiteinteractionsandthebiologicalrolesofcarbohydrates.StructuralanalysisoftheD-man…


Studies on the Total Synthesis of the Repeat Unit of Candida kefyr IFO 0586 Strain
Ping Yu DING, Cheng He ZHOU, Wu Yan ZHANG, Meng Shen CAI. Studies on the Total Synthesis of the Repeat Unit of Candida kefyr IFO 0586 Strain[J]. Chinese Chemical Letters, 1998, 0(9)
Authors:Ping Yu DING   Cheng He ZHOU   Wu Yan ZHANG   Meng Shen CAI
Abstract:The repeat unit of Candida kefyr IFO 0586 strain was designed, and a protectedpentasaccharide was synthesized by thirteen-step reactions. Trichloroacetoxy was used as leavinggroup at anomeric carbon.
Keywords:mannose  glycoside  oligosaccharide  synthesis
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