Synthesis of some new triamide derivatives via Ugi five-component reaction in aqueous solution |
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Authors: | Ali Asghar Mohammadi Salman Taheri Arman Amini Reza Ahdenov |
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Affiliation: | 1.Chemistry Department, Faculty of Sciences,Chemistry and Chemical Engineering Research Center of Iran,Tehran,Iran |
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Abstract: | Triamide derivatives have been synthesized in good yields in a novel, one-pot, five-component, and efficient process by the reaction of Z-oxazolone, water, primary amines, aldehydes, isocyanides, in the presence of catalytic amount of KAl(SO4)2·12H2O (alum) as a non-toxic, reusable, inexpensive, and easily available reagent via Ugi reaction in aqueous solution. |
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