Characterization of microstructured fibre emitters: in pursuit of improved nano electrospray ionization performance |
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Authors: | Wu Xinyun Oleschuk Richard D Cann Natalie M |
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Institution: | Department of Chemistry, Queen's University, Kingston, Ontario, Canada K7L 3N6. natalie.cann@chem.queensu.ca. |
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Abstract: | Full-dimensional computational fluid dynamics (CFD) simulations are presented for nano electrospray ionization (ESI) with various emitter designs. Our CFD electrohydrodynamic simulations are based on the Taylor-Melcher leaky-dielectric model, and the volume of fluid technique for tracking the fast-changing liquid-gas interface. The numerical method is first validated for a conventional 20 μm inner diameter capillary emitter. The impact of ESI voltage, flow rate, emitter tapering, surface hydrophobicity, and fluid conductivity on the nano-ESI behavior are thoroughly investigated and compared with experiments. Multi-electrospray is further simulated with 2-hole and 3-hole emitters with the latter having a linear or triangular hole arrangement. The simulations predict multi-electrospray behavior in good agreement with laboratory observations. |
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