Solution structures of thiopeptide antibiotics |
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| Authors: | Lewis Richard J Hughes Rachael A Alcaraz Lilian Thompson Stewart P Moody Christopher J |
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| Affiliation: | AstraZeneca R&D Charnwood, Bakewell Road, Loughborough, Leicestershire, UK LE11 5RH. |
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| Abstract: | A detailed NMR study of the thiopeptide amythiamicin D establishes its solution conformation and the presence of a single intramolecular hydrogen bond involving NH13 and O28, and also provides the first evidence for self-association of thiopeptides in solution. |
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