| Three-component reaction for synthesis of functionalized spiro[indoline-3,4’-pyrano[3,2-h]quinolines] |
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| 作者姓名： | Rong-Guo Shi Chao-Guo Yan |
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| 作者单位： | College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China |
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| 基金项目： | supported by the National Natural Science Foundation of China (Nos. 21172189, 21572196);the Priority Academic Program Development of Jiangsu Higher Education Institutions |
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| 摘 要： | The functionalized spiroindoline-3,40-pyrano3,2-h]quinolines] were efficiently prepared in high yields from three-component reaction of 8-hydroxyquinoline, isatins and malononitrile or ethyl cyanoacetate in ethanol at room temperature for about 12 h in the presence of piperidine.
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| 关 键 词： | Spirooxindole Chromene Isatin Malononitrile Three-component reaction |
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