Silica-porphyrin hybrid nanotubes for in vivo cell tracking by near-infrared fluorescence imaging |
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| Authors: | Hayashi Koichiro Nakamura Michihiro Ishimura Kazunori |
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| Institution: | Department of Anatomy, Cell Biology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, 770-8503, Japan. khayashi@basic.med.tokushima-u.ac.jp |
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| Abstract: | Near-infrared fluorescent silica-porphyrin hybrid nanotubes (HNTs) were successfully synthesized by π-π stacking, electrostatic interaction and a sol-gel reaction. The HNTs-labeled macrophages were detected in vivo, and the minimum detectable number of cells was 200. Furthermore, the biodistribution of HNTs-labeled macrophages was tracked by fluorescence imaging. |
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