Designing polymeric particles for antigen delivery |
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| Authors: | De Koker Stefaan Lambrecht Bart N Willart Monique A van Kooyk Yvette Grooten Johan Vervaet Chris Remon Jean Paul De Geest Bruno G |
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| Affiliation: | Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Ghent University, Ghent, Belgium. |
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| Abstract: | By targeting dendritic cells, polymeric carriers in the nano to lower micron range constitute very interesting tools for antigen delivery. In this critical review, we review how new immunological insights can be exploited to design new carriers allowing one to tune immune responses and to further increase vaccine potency (137 references). |
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