A new 3,4-dihydroisocoumarin isolated from <Emphasis Type="Italic">Botryosphaeria</Emphasis> sp<Emphasis Type="Italic">.</Emphasis> F00741 |
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| Authors: | Yuhang?Xu Chunhua?Lu Email author" target="_blank">Zhonghui?ZhengEmail author |
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| Institution: | (1) Key Laboratory of the Ministry of Education for Cell Biology and Tumor Cell Engineering, School of Life Sciences, Xiamen University, No. 422 South Siming Road, Xiamen, Fujian, 361005, P. R. China; |
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| Abstract: | A new 3,4-dihydroisocoumarin, named botryoisocoumarin A (1), was obtained from the fermentation culture of Botryosphaeria sp. F00741, together with two known ones, 3,8-dihydroxy-3-methylisochroman-1-one (2) and 4,8-dihydroxy-3-methylisochroman-1-one (3). Their structures were elucidated by spectroscopic analyses, including 1D and 2D NMR experiments and ESI mass spectrometry, and by comparison with those reported. Compound 1 was evaluated for its antitumor and antimicrobial activities in vitro. |
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