Total synthesis of hectochlorin |
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Authors: | Cetusic Jeannie R P Green Frederick R Graupner Paul R Oliver M Paige |
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Affiliation: | Discovery Research, Dow AgroSciences LLC, Indianapolis, IN 46268, USA. jrpcetusic@dow.com |
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Abstract: | Hectochlorin (1) is a marine natural product with significant fungicidal activity. A synthesis effort was initiated to develop a flexible route to hectochlorin which would allow access to analogues with potentially improved activity and/or attributes relative to the natural product. A successful total synthesis of hectochlorin is described. [structure: see text] |
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