A technetium intermediate specifically promotes deprotection of trifluoroacetyl HYNIC during radiolabelling under mild conditions |
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| Authors: | Surfraz M Bashir-Uddin Biagini Stefano C G Blower Philip J |
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| Affiliation: | Cancer Research Group, Department of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK. |
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| Abstract: | The trifluoroacetyl group protects the nucleophilic HYNIC from unwanted side reactions yet allows radiolabelling with technetium-99m under mild conditions, due to efficient and specific promotion of deprotection by a technetium complex intermediate. |
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