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Solvent Effects on Protonation Constants of Imatinib in Different Aqueous Solutions of Methanol at T = 298.15 K
Authors:Tahereh Valizadeh  Kiani  Farhoush  Gharib  Farrokh  Zabihi  Fatemeh  Koohyar  Fardad
Institution:1.Department of Chemistry, Faculty of Science, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
;2.Chemistry Department, Shahid Beheshti University, G.C., Evin, Tehran, Iran
;3.Department of Physics, Faculty of Science, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
;4.Division of Computational Physics, Institute for Computational Science, Ton Duc Thang University, Ho Chi Minh City, Vietnam
;5.Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, Vietnam
;
Abstract:Russian Journal of Physical Chemistry A - Imatinib (Gleevec) is a drug that is applied to treat cancer. It inhibits the Bcr-Abl tyrosine-kinase and therefore, it can slow growth or result in...
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