Covalent hydration of 5-substituted pyrimidines |
| |
| Affiliation: | 1. University of Applied Sciences Inholland, PO Box 3190, 2601 DD Delft, The Netherlands;2. Division of Human Nutrition and Health, Wageningen University, PO Box 17, 6700 AA Wageningen, The Netherlands;1. Key Laboratory of Subsurface Hydrology and Ecological Effects in Arid Region, Chang’an University, Xi’an 710054, PR China;2. School of Environmental Science and Engineering, Chang’an University, Xi’an, 710054, PR China;1. Laboratory of Growth Regulators, The Czech Academy of Sciences, Institute of Experimental Botany & Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic;2. Department of Clinical and Molecular Pathology, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech Republic;3. Isotope Laboratory, The Czech Academy of Sciences, Institute of Experimental Botany, Vídeňská 1083, 142 00 Prague 4, Czech Republic;4. Department of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic;5. Department of Cell Biology, Faculty of Science, Charles University in Prague, Viničná 7, 12843, Prague 2, Czech Republic;1. Department of General Surgery, Taizhou People’s Hospital, Taizhou 225300, PR China;2. Department of Sport and Health Science, Nanjing Sport Institute, Nanjing 210000, PR China;3. Department of Emergency Internal Medicine, Taizhou People’s Hospital, Taizhou 225300, PR China;1. Departments of Internal Medicine, Molecular Genetics and Microbiology and the University of New Mexico Comprehensive Cancer Center, University of New Mexico, Albuquerque, NM 87131, United States;2. Department of Chemistry, Goucher College, Baltimore, MD 21204, United States;3. Department of Chemistry, University of Arkansas at Little Rock, Little Rock, AR 72204, United States |
| |
| Abstract: | 5-Substituted pyrimidines in which the substituent is electron-donating or weakly electron-withdrawing, form normal cations in aqueous acidic solutions. Those in which the substituent is strongly electron-withdrawing form 3,4-hydrated cations, which are usually rather prone to undergo ring cleavage reactions.1H NMR, 13C NMR and u.v. spectroscopy are used in the study. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
