| Abstract: | In this paper some applications of ultracentrifugation on characterizing cationic polypeptides are reviewed. Especially the influence of α-helix favoring, water-structure breaking (chaotropic) anions (e.g. ClO4−) as well as that of strongly hydrated, water structure-making anions (e.g. sulfate) on the sedimentation behaviour of (Lys)n and (Arg)n is considered. Moreover ultracentrifuge studies on the interaction between DNA and strong basic nucleoproteins (protamines) and on the solubilisation of the basic polypeptides mentioned before in reverse micelles are presented. |
