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Total synthesis of glypetelotine
Authors:Xiang Hong Huang  Xu Feng Lin  Su Qin Chenc  Yan Guang Wangb a College of Biology    Environmental Engineering  Zhejiang Shuren University  Hangzhou   PR China b
Affiliation:a College of Biology and Environmental Engineering, Zhejiang Shuren University, Hangzhou 310015, PR China;b Department of Chemistry, Zhejiang University, Hangzhou 310027, PR China;c College of Chemical and Material Engineering, Wenzhou University, Wenzhou 325027, PR China
Abstract:A total synthesis of glypetelotine, the first sulphur-containing indole alkaloid from the leaf extracts of Glycosmis petelotii collected in the north of Vietnam, was described from indole through 6 steps. The structure of the glypetelotine was confirmed by IR, 1H NMR, 13C NMR and MS analysis. The spectral data of synthetic compound was identical with those of natural compound.
Keywords:Sulphur-containing alkaloid  Glypetelotine  Total synthesis  Indole
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