Novel structures of Zn(II) biometal cation with the biologically active substituted acetic acid and nitrogen donor ligands: Synthesis,spectral, phosphate diester catalytic hydrolysis and anti‐microbial studies

The complexes Zn(methoxyacetate)₂1,10‐phenanthroline] 1 and Zn₂(phenylacetate)₄(quinoline)₂] 2 , were prepared and characterized by IR‐spectroscopy, UV–Visible spectroscopy, ¹H and ¹³C NMR spectroscopy, single crystal X‐ray diffraction. BNPP hydrolysis of the complexes and their parent nitrogen ligands were scanned, the results indicated that the hydrolysis rates of BNPP were 4.5 × 10⁴ and 6.2 × 10⁵ for ( 1 ) and ( 2 ), respectively. In addition, anti‐bacterial activities were scanned to investigate the effect of complexation on their activity against Gram‐positive (S. epidermidis , S. aureus , E. faecalis , M. luteus and B. Subtilis ) and Gram‐negative (K. pneumonia , E. coli , P. Mirabilis and P. Aeruginosa ) bacteria using agar well‐diffusion method. Complex 1 showed high activity against G⁻and G ⁺ bacteria except against E. faecalis and P. Aeruginosa . Complex 2 did not show any activity against G⁻ or G ⁺ bacteria.