Amidation through carbamates |
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Authors: | Antonio Latorre Javier Izquierdo |
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Affiliation: | Departament de Química Inorgànica, Universitat Jaume I, 12080 Castelló, Spain |
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Abstract: | N-Alkyl carbamates of primary amines are easily converted into amides under treatment with Grignard reagents. Consequently, primary amines can be converted into amides in a one-pot reaction through carbamate protection and Grignard addition. |
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Keywords: | Amides Carbamates Amines |
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