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TfOH-promoted transformation from 2-alkynylphenyl isothiocyanates to quinoline-2-thiones or indoles
Authors:Takashi Otani
Institution:Department of Chemistry, Faculty of Science, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan
Abstract:A variety of 4-arylquinoline-2-thiones and 3-arylthieno2,3-b]indoles were synthesized in high yields via TfOH-promoted tandem Friedel-Crafts alkenylation-cyclization reactions of 2-alkynylphenyl isothiocyanates.
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