Synthesis and redox-enzyme modulation by amino-1,4-dihydro-benzo[d][1,2]dithiine derivatives |
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| Authors: | Sandraliz Espinosa Cornelis P. Vlaar |
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| Affiliation: | a School of Pharmacy, Medical Sciences Campus, University of Puerto Rico, PO Box 365067, San Juan PR00936, Puerto Rico |
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| Abstract: | A convenient method to prepare a series of benzodithiine derivatives was developed, via the synthesis of cyclic disulfide building blocks containing an amino-group linker. Some of the novel cyclic disulfide compounds are shown to modulate the activity of the redox-enzyme glutathione reductase. |
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