Synthesis of triazole-functionalized tetrahydroindazolones by 1,3-dipolar cycloadditions between azides and alkynes |
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| Authors: | Inta Strakova Andris Strakovs |
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| Institution: | Faculty of Material Science and Applied Chemistry, Riga Technical University, 14/24 Azenes Str., Riga LV-1048, Latvia |
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| Abstract: | 7-Azido-tetrahydroindazolones undergo efficient copper-catalyzed Huisgen 1,3-dipolar cycloaddition reactions with various alkynes leading to a straightforward synthesis of triazole-functionalized tetrahydroindazolones. The latter are interesting molecular platforms in terms of medicinal chemistry. |
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| Keywords: | Tetrahydroindazolones Azides Triazoles Huisgen 1 3-dipolar cycloaddition |
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