Synthesis of fully substituted pyrazolo[3,4-b]pyridine-5-carboxamide derivatives via a one-pot four-component reaction |
| |
| Authors: | Ahmad Shaabani Mozhdeh Seyyedhamzeh Ali Maleki Maryam Behnam Fahimeh Rezazadeh |
| |
| Affiliation: | Department of Chemistry, Shahid Beheshti University, PO Box 19396-4716, Tehran, Iran |
| |
| Abstract: | A one-pot four-component reaction of an aliphatic or aromatic amine, diketene, an aromatic aldehyde and 1,3-diphenyl-1H-pyrazol-5-amine in the presence of p-toluenesulfonic acid as a catalyst has been developed. In this reaction, a new class of fully substituted pyrazolo[3,4-b]pyridine-5-carboxamide derivatives is produced under mild reaction conditions and in good yields at ambient temperature. |
| |
| Keywords: | Pyrazolo[3,4-b]pyridine-5-carboxamide Multicomponent reaction One-pot 1,3-Diphenyl-1H-pyrazol-5-amine Diketene |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
