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Efficient synthesis of esters containing tertiary amine functionalities via active cyanomethyl ester intermediates
Authors:Camille Bouillon  Ling Peng
Institution:Centre Interdisciplinaire de Nanoscience de Marseille, CNRS UPR 3118, Department of Chemistry, Faculty of Sciences of Luminy, Aix-Marseille Université, 13288 Marseille Cedex 9, France
Abstract:Esters containing tertiary amine functionalities were successfully synthesized under mild conditions and in good yields, using a three-step process involving the activation of acids into their corresponding cyanomethyl esters, followed by transesterification with the alcohol counterparts, and subsequent scavenging of the excess of alcohol to facilitate purification.
Keywords:Tertiary amine-containing esters  Cyanomethyl ester  Transesterification  Scavenging
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