Efficient synthesis of esters containing tertiary amine functionalities via active cyanomethyl ester intermediates |
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Authors: | Camille Bouillon Ling Peng |
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Institution: | Centre Interdisciplinaire de Nanoscience de Marseille, CNRS UPR 3118, Department of Chemistry, Faculty of Sciences of Luminy, Aix-Marseille Université, 13288 Marseille Cedex 9, France |
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Abstract: | Esters containing tertiary amine functionalities were successfully synthesized under mild conditions and in good yields, using a three-step process involving the activation of acids into their corresponding cyanomethyl esters, followed by transesterification with the alcohol counterparts, and subsequent scavenging of the excess of alcohol to facilitate purification. |
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Keywords: | Tertiary amine-containing esters Cyanomethyl ester Transesterification Scavenging |
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