Binary and ternary chromium(III) complexes with cellular reductants and DNA components isolated from redox type systems. Part 2. Chromium(VI)—glutathione—adenine (adenosine,ATP)

The reduction of CrO₃ with an excess of glutathione and its interaction with DNA fragments (adenine, adenosine) and the ATP nucleotide was studied by analysis of the isolated solid products. The precipitates were characterised by elemental analyses, FAB-mass spectral data, spectroscopic methods (u.v.–vis., i.r., f.i.r.) and magnetic measurements. The Cr^III complexes obtained from ternary systems appeared to be [Cr^III—glutathione] and [Cr^III—glutathione—adenine (adenosine, ATP)] species. The structure of the complexes has been proposed assuming hydrogen bonding between the Cr^III GSH complex and the DNA fragment.