New liquid chromatography/electron ionization mass spectrometry methods in water analysis |
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Authors: | Cappiello Achille Famiglini Giorgio Berloni Arnaldo Palma Pierangela Mangani Filippo |
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Institution: | Istituto di Scienze Chimiche F. Bruner, Università di Urbino, P. Rinascimento 6, 61029 Urbino. achille@uniurb.it |
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Abstract: | A method to extract and analyze organic compounds from water is presented. A solid phase micro-trap (micro-SPE) directly connected to the micro-analytical column is used. Sensibility and specificity needed for trace analysis are guaranteed by mass spectrometric electron ionization (EI) detection. A new micro-HPLC/EI-MS interface called Capillary-EI (Cap-EI) is described. The ultimate evolution of this interface is also presented: in this extremely simplified interface the analytes are nebulized, vaporized and ionized in the small volume of the ion source. This interface, called Direct-EI, exploits nano- and micro-HPLC columns with a mobile phase flow rates ranging from 0.3 to 1.5 microL/min. Contemporary use of micro SPE, Cap-EI or Direct-EI gives us a powerful technique to identify and quantify organic pollutants at part per billion level (ppb). |
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