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Pyridinium tribromide catalyzed condensation of indoles and aldehydes to form bisindolylalkanes
Authors:Qin Yang  Zheng Lan Yina  Ban Lai Ouyanga  Yi Yuan Peng a Key Laboratory of Green Chemistry  Jiangxi Province  College of Chemistry  Jiangxi Normal University  Nanchang  China b Key Laboratory of Small Fuctional Organic Molecule  Ministry of Education  College of Life Science  China
Institution:a Key Laboratory of Green Chemistry, Jiangxi Province and College of Chemistry, Jiangxi Normal University, Nanchang 330022, China;b Key Laboratory of Small Fuctional Organic Molecule, Ministry of Education and College of Life Science, Jiangxi Normal University, Nanchang 330022, China
Abstract:An efficient synthetic method for bis(indol-3-yl)alkane derivatives has been developed.In the presence of 5 mol%of pyridinium tribromide(PTB),the condensation of indoles and aldehydes proceeded smoothly under mild conditions,giving rise to the corresponding bis(indol-3-yl)alkanes in good to excellent yields.
Keywords:Pyridinium tribromide  Indole  Aldehyde  Bis(indol-3-yl)alkane  
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