P-Dodecylbenzenesulfonic acid(DBSA),a Brфnsted acid-surfactant catalyst for Biginelli reaction in water and under solvent free conditions |
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作者姓名: | Mohammad Ali Bigdeli Ghazaleh Gholami Enayatollah Sheikhhosseini |
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作者单位: | Faculty of Chemistry, Tarbiat Moallem University, 49 Mofateh, Tehran, Iran |
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基金项目: | the faculty of chemistry of Tarbiat Moallem University for supporting this work |
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摘 要: | We report herein the use of p-dodecylbenzenesulfonic acid(DBSA) as a catalyst for a one-pot Biginelli reaction to afford 3,4- dihydropyrimidinone derivatives in good to excellent yields.This reaction proceeds efficiently in water and under solvent free conditions.Comparisons of results indicate that although the yields are high and comparable for both methods,the reaction times are considerably shorter under solvent free conditions.
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关 键 词: | Biginclli reaction Dihydropyrimidinonc P-Dodecylbenzenesulfonic acid(DBSA) |
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