Synthesis of isoquinoline derivatives using ROM-RCM of cyclobutene-yne |
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| Authors: | Mori Miwako Wakamatsu Hideaki Tonogaki Keisuke Fujita Reiko Kitamura Tsuyoshi Sato Yoshihiro |
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| Affiliation: | Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan. mori@pharm.hokudai.ac.jp |
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| Abstract: | Isoquinoline derivatives were synthesized from cyclobutenylmethylamine derivatives having an alkyne moiety in a tether using a second-generation ruthenium carbene complex under ethylene gas in good yields. |
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