An efficient route to 1-aminoisoquinolines via AgOTf-catalyzed reaction of 2-alkynylbenzaldoxime with amine |
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| Authors: | Zheng Danqing Chen Zhiyuan Liu Jianping Wu Jie |
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| Affiliation: | Department of Chemistry, Fudan University, 220 Handan Road, Shanghai, 200433, China. |
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| Abstract: | 2-Alkynylbenzaldoxime reacts with amine catalyzed by silver triflate under mild conditions, leading to 1-aminoisoquinolines in good yield. This reaction proceeds efficiently with good functional group tolerance. |
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