Fluctuating Diffusivity of RNA-Protein Particles: Analogy with Thermodynamics |
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Authors: | Yuichi Itto |
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Affiliation: | 1.Institut für Computerphysik, Universität Stuttgart, 70569 Stuttgart, Germany; or ;2.Science Division, Center for General Education, Aichi Institute of Technology, Aichi 470-0392, Japan |
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Abstract: | A formal analogy of fluctuating diffusivity to thermodynamics is discussed for messenger RNA molecules fluorescently fused to a protein in living cells. Regarding the average value of the fluctuating diffusivity of such RNA-protein particles as the analog of the internal energy, the analogs of the quantity of heat and work are identified. The Clausius-like inequality is shown to hold for the entropy associated with diffusivity fluctuations, which plays a role analogous to the thermodynamic entropy, and the analog of the quantity of heat. The change of the statistical fluctuation distribution is also examined from a geometric perspective. The present discussions may contribute to a deeper understanding of the fluctuating diffusivity in view of the laws of thermodynamics. |
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Keywords: | analogy with thermodynamics fluctuating diffusivity RNA-protein particles |
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