Petasis vs. Strecker Amino Acid Synthesis: Convergence,Divergence and Opportunities in Organic Synthesis |
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Authors: | Wayiza Masamba |
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Institution: | Department of Chemical and Physical Sciences, Faculty of Natural Sciences, Walter Sisulu University, Nelson Mandela Drive, Mthatha 5117, South Africa; |
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Abstract: | α-Amino acids find widespread applications in various areas of life and physical sciences. Their syntheses are carried out by a multitude of protocols, of which Petasis and Strecker reactions have emerged as the most straightforward and most widely used. Both reactions are three-component reactions using the same starting materials, except the nucleophilic species. The differences and similarities between these two important reactions are highlighted in this review. |
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Keywords: | amino acids biomolecules multicomponent reactions peptides Petasis Strecker |
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