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Label-free fluorescent detection of Cu(II) ions based on DNA cleavage-dependent graphene-quenched DNAzymes |
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| Authors: | Liu Meng Zhao Huimin Chen Shuo Yu Hongtao Zhang Yaobin Quan Xie |
| Affiliation: | Key Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education, China), School of Environmental Science and Technology, Dalian University of Technology, Dalian, 116024, China. |
| Abstract: | We developed a novel and general methodology to design a label-free fluorescent Cu(II) sensor based on internal DNA cleavage and an extrinsic fluorophore in a graphene/DNAzymes complex with high sensitivity and selectivity. |
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