| 纤维素三(3, 5-二硝基)苯甲酸酯手性固定相的制备和应用研究 |
| |
| 引用本文： | 邹公伟,郑琦,胡冠九,邵宇,施耀曾. 纤维素三(3, 5-二硝基)苯甲酸酯手性固定相的制备和应用研究[J]. 化学学报, 1997, 55(6): 617-621 |
| |
| 作者姓名： | 邹公伟 郑琦 胡冠九 邵宇 施耀曾 |
| |
| 作者单位： | 南京大学化学系.南京(210008) |
| |
| 基金项目： | 国家自然科学基金资助的项目 |
| |
| 摘 要： | 纤维素三(3,5-二硝基)苯甲酸酯用超声反应合成,具有反PirkleI型手性固定相的结构,将其涂布在大孔硅胶载体上,用作一种新的高效液相色谱手性固定相,成功地拆分了布洛芬和氰戊菊酯的中间体。讨论了其分离的机理。
|
| 关 键 词： | 应用 制备 手性固定相 苯甲酸酯 纤维素 三苯甲酯 氰戊菊酯 布洛芬 消旋体拆分 超声反应 |
Study on the preparation and application of cellulose tris(3, 5- dinitro) benzoate as chiral stationary phase |
| |
| Zou Gongwei,Zheng Qi,Hu Guanjiu,Shao Yu,Shi Yaozeng. Study on the preparation and application of cellulose tris(3, 5- dinitro) benzoate as chiral stationary phase[J]. Acta Chimica Sinica, 1997, 55(6): 617-621 |
| |
| Authors: | Zou Gongwei Zheng Qi Hu Guanjiu Shao Yu Shi Yaozeng |
| |
| Affiliation: | Nanjing Univ, Dept Chem.Nanjing(210008) |
| |
| Abstract: | Cellulose tris(3, 5-dinitro) benzoate (CTNB) was ultra-sonically synthesized as a reversed Pirkle chiral stationary phase (CSP) type I. After coating on macroporous silica gel, the chiral separation ability was studied as HPLC CSP. The resolution of ibuprofenum was performed with γ=1.25, the resolution of an esfenvalerate intermediate was also achieved (γ=1.39). The mechanism and model of separation were discussed. |
| |
| Keywords: | APPLICATION PREPARATION BENZOIC ETHER CELLULOSE FENVALERATE IBUPROFEN MESOTOMY |
| 本文献已被 CNKI 维普 等数据库收录！ |
| 点击此处可从《化学学报》浏览原始摘要信息 |
|
点击此处可从《化学学报》下载全文 |
|
