Application of a flow-tunable, serially coupled gas chromatographic capillary column system for the analysis of complex mixtures |
| |
Authors: | F Garay |
| |
Institution: | (1) IEM Institute for Environmental Protection, P.O. Box 352, 1369 Budapest, Hungary |
| |
Abstract: | Summary A capillary column gas chromatographic system employing two serially coupled fused-silica columns and a simple coupling element
is described. The system is operated in flow-tunable mode (flow-tunable tandem system).
The very fact of continuous tuning over a large polarity (selectivity) range, ultimately determined by the two constituent
columns, offers several possibilities in the analysis of complex mixtures. In this paper two applications are discussed in
detail: optimization of peak separation and peak identification. For these applications it is feasible to use, retention data
collected from experiments on the tandem system, and empirical formulas. A relatively simple theoretical mathematical model
valid for the flow-tunable tandem system, however, furnishes an easy way of calculating retention data on the system from
data collected from the individual single columns, thus, creating a new possibility for optimization and peak identification.
Optimization and peak identification processes using the empirical and theoretical models are both demonstrated by analysis
of solvent mixtures.
Dedicated to the memory of Dr. Tibor Tóth
Presented at Balaton Symposium on High-Performance Separation Methods, Siófok, Hungary, September 1–3, 1999 |
| |
Keywords: | Capillary gas chromatography Serially coupled columns Polarity/selectivity tuning by flow Retention index calculation Component identification Optimizing peak separation |
本文献已被 SpringerLink 等数据库收录! |
|