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| 3-(2-二唑啉基)-色酮类化合物的合成研究 | |
| 引用本文： | 于建新,刘方明,鲁文杰,李燕萍,糟新民,刘育亭,刘丛. 3-(2-二唑啉基)-色酮类化合物的合成研究[J]. 有机化学, 2000, 20(1) |
| 作者姓名： | 于建新 刘方明 鲁文杰 李燕萍 糟新民 刘育亭 刘丛 |
| 作者单位： | 1. 新疆大学化学系,乌鲁木齐830046 2. 广东江门五邑大学 3. 新疆师范大学化学系,乌鲁木齐830011 |
| 基金项目： | 国家自然科学基金(批准号:29862005)，新疆大学自然科学基金 |
| 摘 要： | 报道了取代的邻羟基苯乙酮(1a～1e)经Vilsmeier-Haack反应一步制得3-醛基色酮(2a～2e),2a～2e与取代的芳酰肼(3a～3c)缩合制得15个酰腙类化合物(4a～4o),4a～4o在醋酸酐作用下关环得15个3-(2-苝二唑啉基)-色酮(5a～5o),并通过元素分析,IR,~1H NMR和MS诺数据确证了上述化合物的结构。 |
| 关 键 词： | Vilsmeier-Haack反应 色酮 噁二唑啉 |
Synthesis of Some Substituted 3 - (3'- Acetyl - 5'- Aryl -1', 3', 4' - Oxadiazoline - 2' - yl) - Chromones |
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| YU Jian-Xin,LIU Fang-Ming,LU Wen-Jie,LI Yan-Ping,ZAO Xin-Min,LIU Yu-Ting,LIU Cong. Synthesis of Some Substituted 3 - (3'- Acetyl - 5'- Aryl -1', 3', 4' - Oxadiazoline - 2' - yl) - Chromones[J]. Chinese Journal of Organic Chemistry, 2000, 20(1) | |
| Authors: | YU Jian-Xin LIU Fang-Ming LU Wen-Jie LI Yan-Ping ZAO Xin-Min LIU Yu-Ting LIU Cong |
| Abstract: | By the Vilsmeier - Haack reaction, chromone - 3 - carboxaldehydes(2a - 2e) were prepared in high yields, whichreacted regiospecifically with substituted aroyl hydrazines(3a - 3c) in EtOH containing AcOH at room temperature to give 3 - (substituted aroyl hydrazone)chromones(4a - 4o). 4a- 4o could be readily converted to substituted 3 - ( 3 - acetyl - 5 - aryl - 1,3,4- oxadiazoline - 2 ( - yl) - chromones (5a- 5o) in good yields by refluxing with Ac2O. Their structures were established by elemental analysis, IR.1H NMR and MS spectra. |
| Keywords: | Vilsmeier- Haack reaction Chromones 1 3 4 - oxadiazoline |
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