Controlling 3(10)-helix and alpha-helix of short peptides in the solid state |
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Authors: | Demizu Yosuke Tanaka Masakazu Nagano Masanobu Kurihara Masaaki Doi Mitsunobu Maruyama Tokumi Suemune Hiroshi |
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Affiliation: | Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka 812-8582, Japan. |
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Abstract: | L-Leu hexapeptide containing alpha-aminoisobutyric acid (Aib) forms a right-handed (P) 3(10)-helix, whereas that containing cyclic alpha,alpha-disubstituted amino acid Ac(5)c(dOM) assumes a right-handed (P) alpha-helix in the solid state. |
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