| 双步激光解析/激光电离质谱法及其应用的新进展 |
| |
| 引用本文： | 王红磊,胡勇军,邢达. 双步激光解析/激光电离质谱法及其应用的新进展[J]. 分析化学, 2011, 39(2): 276-282. DOI: 10.3724/SP.J.1096.2011.00276 |
| |
| 作者姓名： | 王红磊 胡勇军 邢达 |
| |
| 作者单位： | 华南师范大学生物光子学研究院激光生命科学研究所暨激光生命科学教育部重点实验室,广州,510631 |
| |
| 基金项目： | 国家自然科学基金(No.20973067); 广州市科技计划项目(穗科条字【2009】6号); 高等学校人才引进专项资金(粤财教【2009】109号)资助 |
| |
| 摘 要： | 激光光电离技术已广泛应用于质谱领域.基于单束激光的基质辅助激光解析(MALDI)质谱分析方法,已成为质谱分析生物大分子的标准方法之一.本文介绍的是另一种新的激光质谱分析方法:双步激光解析/激光电离质谱法(L2MS),与MALDI相比,该方法不需要加入与样品形成共结晶的基质,同时可通过独立地改变两束激光的光强和波长达到优...
|
| 关 键 词： | 光电离 激光解析 质谱分析 生物技术 多环芳烃 综述 |
Recent Progress of Two-step Laser Desorption/Laser Ionization Mass Spectrometry and Its Application |
| |
| WANG Hong-Lei,HU Yong-Jun,XING Da. Recent Progress of Two-step Laser Desorption/Laser Ionization Mass Spectrometry and Its Application[J]. Chinese Journal of Analytical Chemistry, 2011, 39(2): 276-282. DOI: 10.3724/SP.J.1096.2011.00276 |
| |
| Authors: | WANG Hong-Lei HU Yong-Jun XING Da |
| |
| Affiliation: | WANG Hong-Lei,HU Yong-Jun*,XING Da (Ministry of Education Key Laboratory of Laser Life Science & Institute of Laser Life Science,College of Biophotonics,South China Normal University,Guangzhou 510631) |
| |
| Abstract: | As a particular ionization technology,laser photoionization has been widely used in the field of the mass spectroscopy.Matrix assisted laser desorption ionization(MALDI),where only one laser is used,has become the standard method in the biological mass spectrometry.In this review,a new mass spectrometric method based on two lasers is introduced,i.e.,Two-step laser desorption/laser ionization mass spectrometry(L2MS).Comparing this method with MALDI,no matrix is needed to add on the substrate to form a good c... |
| |
| Keywords: | Photoionization Laser Desorption Mass spectroscopy Biological technique Polycyclic aromatic hydrocarbons Review |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
