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Pyrazolidine derivatives with heteroaryl urea as dipeptidyl peptidase IV inhibitors |
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| Authors: | Ahn Jin Hee Jung Sun Ho Kim Jin Ah Song Seog Beom Kwon Soon Ji Kim Kwang Rok Rhee Sang Dal Park Sung-Dae Lee Jae Mok Kim Sung Soo Cheon Hyae Gyeong |
| Affiliation: | Medicinal Science Division, Korea Research Institute of Chemical Technology, Taejon 305-600, Korea. jhahn@krict.re.kr |
| Abstract: | In the continuation of efforts to modify the structure of our novel DP-IV inhibitors, a series of pyrazolidine derivatives with heteroaryl urea was synthesized and evaluated for their ability to inhibit dipeptidyl peptidase IV (DP-IV). |
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