Effects of local electric fields on the redox free energy of single stranded DNA |
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Authors: | D'Abramo Marco Orozco Modesto Amadei Andrea |
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Affiliation: | Departamento de Bioquímica y Biología Molecular Universitat de Barcelona, Barcelona, Spain. marco.dabramo.cnio@gmail.com |
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Abstract: | Influence of external electric field as well as base substitution effects on the reduction/oxidation free energies of single stranded DNA suggest that base sequencing via measuring redox properties might be feasible under the conditions that (i) a difference of ~ 230 kJ mol(-1) in the oxidation potentials is enough to discriminate between nucleobases conductance signals and (ii) the strand is long enough to reduce end effects. |
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