J‐Edited Pure Shift NMR for the Facile Measurement of nJHH for Specific Protons |
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Authors: | Dr Sachin Rama Chaudhari Prof N Suryaprakash |
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Institution: | NMR Research Centre and Solid State Structural Chemistry Unit, Indian Institute of Science, Bangalore 560012 (India), Fax: (+81) 8023601550 |
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Abstract: | We report a novel 1D J‐edited pure shift NMR experiment (J‐PSHIFT) that was constructed from a pseudo 2D experiment for the direct measurement of proton–proton scalar couplings. The experiment gives homonuclear broad‐band 1H‐decoupled 1H NMR spectra, which provide a single peak for chemically distinct protons, and only retain the homonuclear‐scalar‐coupled doublet pattern at the chemical‐shift positions of the protons in the coupled network of a specific proton. This permits the direct and unambiguous measurement of the magnitudes of the couplings. The incorporation of a 1D selective correlation spectroscopy (COSY)/ total correlation spectroscopy (TOCSY) block in lieu of the initial selective pulse, results in the exclusive detection of the correlated spectrum of a specific proton. |
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Keywords: | analytical methods broadband decoupling homonuclear scalar couplings NMR spectroscopy pure shift spectra |
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