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OPLS in batch monitoring – Opens up new opportunities
Authors:Nabil Souihi  Anders Lindegren  Lennart Eriksson  Johan Trygg
Institution:1. Computational Life Science Cluster (CLiC), Department of Chemistry, Umeå University, Sweden;2. MKS Umetrics, Umeå, Sweden
Abstract:In batch statistical process control (BSPC), data from a number of “good” batches are used to model the evolution (trajectory) of the process and they also define model control limits, against which new batches may be compared. The benchmark methods used in BSPC include partial least squares (PLS) and principal component analysis (PCA).
Keywords:Batch statistical process control  Orthogonal projections to latent structures  Process chemometrics  Multivariate statistical process control
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