Effect of the silica content on the physico-chemical and relaxation properties of hybrid polymer/silica nanocomposites of P(EMA-co-HEA) |
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Authors: | A Vallés-Lluch G Gallego Ferrer M Monleón Pradas |
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Institution: | a Center for Biomaterials and Tissue Engineering, Universidad Politécnica de Valencia, Cno. de Vera s/n, 46022 Valencia, Spain b Regenerative Medicine Unit, Centro de Investigación Príncipe Felipe, Av. Autopista del Saler 16, 46013 Valencia, Spain c Networking Research Center on Bioengineering, Biomaterials and Nanomedicine, Valencia, Spain |
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Abstract: | Poly(ethyl methacrylate-co-hydroxyethyl acrylate) 70/30 %wt/silica, P(EMA-co-HEA)/SiO2, nanocomposites, with silica contents ranging from 0 to 30 %wt, were synthesized and studied as promising candidate materials for the synthetic matrix of scaffolds for bone substitutes or dentin regeneration. The physico-chemical properties of the hybrids were studied by calorimetry and by contact angle measurements on the surfaces. The dynamic-mechanical and compression properties were analysed. Intermediate silica contents in the range from 10 to 20 %wt of silica rendered co-continuous interpenetrated structures, in which silica produced a reinforcing effect in the polymeric matrix and at the same time conferred bioactivity to the surfaces by improving surface wettability, making these hybrids appropriate for the proposed application. On the contrary, silica percentages below 10 %wt formed disconnected inorganic aggregates at the nanoscale dispersed in the copolymer matrix, which did not modify significantly the copolymer properties. Silica contents above 20 %wt formed denser inorganic networks with few terminal silanol groups available at the surfaces, much more rigid and hardly manageable samples. |
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Keywords: | Nanocomposite Acrylate Silica Sol-gel Bioactivity |
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