A flow cytometry-based dopamine transporter binding assay using antagonist-conjugated quantum dots |
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| Authors: | Kovtun Oleg Ross Emily J Tomlinson Ian D Rosenthal Sandra J |
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| Affiliation: | Department of Chemistry, Vanderbilt University, 7300 Stevenson Ctr Ln, Nashville, TN 37235, USA. |
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| Abstract: | Here we present the development and validation of a flow cytometry-based dopamine transporter (DAT) binding assay that uses antagonist-conjugated quantum dots (QDs). We anticipate that our QD-based assay is of immediate value to the high throughput screening of novel DAT modulators. |
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