Hydroboration with pyridine borane at room temperature |
| |
Authors: | Clay Julia M Vedejs Edwin |
| |
Affiliation: | Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA. |
| |
Abstract: | Treatment of pyridine borane (Py.BH3) with iodine, bromine, or strong acids affords activated Py.BH2X complexes that are capable of hydroborating alkenes at room temperature. Evidence is presented for an unusual hydroboration mechanism involving leaving group displacement. In contrast to THF.BH3, hydroboration with Py.BH2I selectively affords the monoadducts. The crude hydroboration products are converted into synthetically useful potassium alkyltrifluoroborate salts upon treatment with methanolic KHF2. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|