Synthesis of Chiral 1,3-Bis(oxazolinyl)benzene

In recent years, C₂-symmetric chiral bis (oxazoline) ligand-metal complexes have received a great of attention through their use in various catalytic processes^1-2]. Since the early 1990s, many impressive enantioselective carbon-carbon bond forming reactions, aziridination reactions, hydrosilylations, oxidations and reductions have been recorded using bis (oxazoline)-metal complexes with wide structural diversity^3-4]. The latest review is intended to focus on the recent developments of bis(oxazoline) ligand-metal catalyzed asymmetric reactions and their applications in organic synthesis. Herein we intend to report the synthesis of a new type of chiral bis(oxazoline), 1,3-bis(oxazolinyl)benzene. Application of their asymmetric catalysis is under working.