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Structural features of the Cu(II) complex with the rat Abeta(1-28) fragment
Authors:Gaggelli Elena  Grzonka Zbigniew  Kozłowski Henryk  Migliorini Caterina  Molteni Elena  Valensin Daniela  Valensin Gianni
Institution:Department of Chemistry, University of Siena, via Aldo Moro, 53100 Siena, Italy.
Abstract:The interaction between Cu(II) and the rat amyloid beta (1-28) fragment in micellar solutions at pH 7.5 was investigated by CD and NMR spectroscopy; the proton-copper distances were used in restrained molecular dynamics simulations to obtain a structural model of the Cu(II) complex.
Keywords:
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