| 纳米抗癌药物载体的研究进展 |
| |
| 引用本文： | 郑楠,郑玉斌. 纳米抗癌药物载体的研究进展[J]. 高分子通报, 2011, 0(9): 176-183 |
| |
| 作者姓名： | 郑楠 郑玉斌 |
| |
| 作者单位： | 大连理工大学化工与环境生命学部高分子材料系辽宁省高分子科学与工程重点实验室,大连,116024 |
| |
| 摘 要： | 与传统抗癌药物相比，纳米抗癌药物载体具有可在体内实现长循环，于癌症组织处富集，在体内缓慢可控释放，药物利用率高，药效高，并且生物相容性与可降解性良好的优点。目前已经实现包括纳米微粒、纳米胶束、树枝状大分子等多种结构的纳米抗癌药物载体的设计，选用的药物载体材料也涵盖多种聚酯以及蛋白质多肽等生物相容性良好的材料。
|
| 关 键 词： | 纳米抗癌药物载体 可控释放 生物相容性 |
Research Progression of Nanoanti-cancer Drug Carrier |
| |
| Zheng Nan,ZHENG Yu-bin. Research Progression of Nanoanti-cancer Drug Carrier[J]. Polymer Bulletin, 2011, 0(9): 176-183 |
| |
| Authors: | Zheng Nan ZHENG Yu-bin |
| |
| Affiliation: | Zheng Nan,ZHENG Yu-bin*(Liaoning Province Key Laboratory of Polymer Science and Engineering,Department of Polymer Science and Engineering,School of Chemical Engineering,Dalian University of Technology,Dalian 116024,China) |
| |
| Abstract: | Compared with traditional anticancer drug,nanoanticancer drug carrier has the advantage of long circulation in vito,targeted to the tumor organization,controlled release increased therapeutic effects and efficiency,reduced toxicity and good biocompatibility and biodegradability.Now scientists have successfully design and synthesize different kinds of anticancer drug carrier including the structures of nano-particle,nano-micelle and dendrimer.Different kinds of polyester,protein and polypeptides,which are al... |
| |
| Keywords: | Nanoanticancer durg carrier Controlled release Biocompatibility |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
