This paper is concerned with the existence of positive solutions of the third-order boundary value problem with full nonlinearity
$$\begin{aligned} \left\{ \begin{array}{lll} u'''(t)&{}=f(t,u(t),u'(t),u''(t)),\quad t\in 0,1],\\ u(0)&{}=u'(1)=u''(1)=0, \end{array}\right. \end{aligned}$$
where
\(f:0,1]\times \mathbb {R}^+\times \mathbb {R}^+\times \mathbb {R}^-\rightarrow \mathbb {R}^+\) is continuous. Under some inequality conditions on
f as |(
x,
y,
z)| small or large enough, the existence results of positive solution are obtained. These inequality conditions allow that
f(
t,
x,
y,
z) may be superlinear, sublinear or asymptotically linear on
x,
y and
z as
\(|(x,y,z)|\rightarrow 0\) and
\(|(x,y,z)|\rightarrow \infty \). For the superlinear case as
\(|(x,y,z)|\rightarrow \infty \), a Nagumo-type growth condition is presented to restrict the growth of
f on
y and
z. Our discussion is based on the fixed point index theory in cones.