An easy access to 2-Amino-5,6-dihydro-3H-pyrimidin-4-one building blocks: The reaction under conventional and microwave conditions |
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| Authors: | Konstantin S. Ostras Nikolay Yu. Gorobets Sergey M. Desenko Vladimir I. Musatov |
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| Affiliation: | (1) Department of Heterocyclic Compounds, State Scientific Institution ‘Institute for Single Crystals’ of National Academy of Sciences of Ukraine, Lenin Ave 60, Kharkiv, 61001, Ukraine |
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| Abstract: | Summary A new one-stage fast multicomponent synthesis of title compounds leads to products in 21–55% isolated yields under both conventional and microwave conditions. The primary amino group in the building blocks can be easily acylated by various usual electophilic agents that can be utilized in the synthesis of diverse heterocylic compounds libraries. |
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| Keywords: | dihydropyrimidines building blocks multicomponent reaction microwave library synthesis |
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